On March 21, Nature published a breakthrough study by a Chinese research team online, which reported a new method to convert 8C-like cells (8CLC) from human pluripotent stem cells (PSC).

As totipotent stem cells in early development, 8C-like cells (8CLC) can differentiate into all types of cells within placental tissue embryonic tissues but also have the potential to develop into more mature tissues and organs. The experiments described by the study demonstrated the totipotency of these cells.

The study was the first to demonstrate that converted cells can produce placental tissues in vivo. Understanding totipotency in human cells would have very broad implications in regenerative medicine in terms of helping to regenerate human organs, reducing dependence on organ donation, and generating artificial blastocysts and blastocysts. The research method used in the study will also help scientists unravel the secrets of embryogenesis and treat diseases associated with human embryonic development.

CAST is the largest non-governmental organization of scientific and technological professionals in the world. Through its 211 member societies and local branches all over the country, CAST maintains close ties with millions of Chinese scientists, engineers, and other professionals working in fields of science and  technology.

Source: www.cast.org.cn